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From the Lehigh Valley:
Route 33 North to I-80 West to Exit 299 (old Exit 45) Tannersville, and follow the signs to Camelback (alternate exit 298).

From Scranton:
I-380 South to I-80 East to Exit 299 (old Exit 45) Tannersville, and follow the signs to Camelback (alternate exit 298).

From Wilkes-Barre:
I-476 (NE Extension of the PA Turnpike) South or Route 115 South to I-80 East to Exit 299 (old Exit 45) Tannersville. Follow signs to Camelback (alternate exit 298).

From Philadelphia & South of Philadelphia
I-476 (NE Extension of the PA Turnpike) North to Lehigh Valley Exit 56 (old Exit 33), Route 22 East to Route 33 North to I-80 West to Exit 299 (old Exit 45) Tannersville, and follow the signs to Camelback (alternate exit 298).

From Metropolitan New Jersey & New York:
I-80 West to PA Exit 299 (old Exit 45) Tannersville, and follow the signs to Camelback (alternate exit 298).

From Central NJ, Newark, and Southern Metro New York City Area:
I-78 West to PA Route 33 North to I-80 West to Exit 299 (old Exit 45) Tannersville, and follow the signs (alternate exit 298).